产品英文名称 | TGFβ1 Polyclonal Antibody |
产品中文名称 | 转化生长因子β1多克隆抗体 |
别名 | TGFB1; TGFB; Transforming growth factor beta-1; TGF-beta-1 |
克隆类型 | 多克隆 |
检测类型 | WB |
反应性 | 人,大鼠,小鼠 |
宿主 | 兔 |
浓度 | 1 mg/ml |
免疫原 | 合成多肽:来源于C端的人源蛋白TGFβ1. 氨基酸序列为: 310-390 |
样本类型 | WB# IHC-p# IF# ELISA |
产品形式 | 液体形式 |
基因ID | 7040 |
目标条带分子量 | 44 |
蛋白序列链接 | http://www.uniprot.org/uniprot/P01137 |
存储缓冲液 | 含有50%甘油,0.5%BSA和0.02%叠氮化钠的PBS缓冲液。 |
保存建议 | 自发货之日起,-20°C可稳定保存1年。为最大限度的避免损失,请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。 |
运输条件 | 蓝冰运输 |
警告 | 本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。 |
其他 | 该抗体可检测内源蛋白 |
背景 | TGFB1 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. The Transforming growth factor beta-1 regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. |
Fig.1. Western Blot analysis of various cells using TGFβ1 Polyclonal Antibody diluted at 1:2000.|||ABP52598-2.jpg
作者:Jia, Peizhi, et al. 杂志名称:Journal of Ethnopharmacology IF:5
作者:Wen, Ying, et al. 杂志名称:Frontiers in Pharmacology IF:6
作者:Jia, Peizhi, et al. 杂志名称:Journal of Ethnopharmacology IF:5
作者:P Jia, D Chen, Y Zhu, M Wang, J Zeng, L Zhang 杂志名称:Journal of Ethnopharmacology IF:5
作者:Zeng, Weiquan, et al. 杂志名称:Biomedicine & Pharmacotherapy IF:8
作者:Wen, Ying, et al. 杂志名称:Frontiers in Pharmacology IF:6
作者:P Jia, D Chen, Y Zhu, M Wang, J Zeng, L Zhang 杂志名称:Journal of Ethnopharmacology IF:5
作者:Zeng, Weiquan, et al. 杂志名称:Biomedicine & Pharmacotherapy IF:8