| 产品英文名称 | SREBP-1 Polyclonal Antibody |
| 产品中文名称 | 固醇调控元件结合转录因子1多克隆抗体 |
| 别名 | SREBF1; BHLHD1; SREBP1; Sterol regulatory element-binding protein 1; SREBP-1; Class D basic helix-loop-helix protein 1; bHLHd1; Sterol regulatory element-binding transcription factor 1 |
| 克隆类型 | 多克隆 |
| 检测类型 | WB |
| 反应性 | 人,大鼠,小鼠 |
| 宿主 | 兔 |
| 浓度 | 1 mg/ml |
| 免疫原 | 合成多肽：来源于中间区域的人源蛋白SREBP-1. |
| 样本类型 | WB# ELISA |
| 产品形式 | 液体形式 |
| 基因ID | 6720 |
| 目标条带分子量 | 120 |
| 蛋白序列链接 | http://www.uniprot.org/uniprot/P36956 |
| 存储缓冲液 | 含有50％甘油，0.5％BSA和0.02％叠氮化钠的PBS缓冲液。 |
| 保存建议 | 自发货之日起，-20°C可稳定保存1年。为最大限度的避免损失，请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。 |
| 运输条件 | 蓝冰运输 |
| 警告 | 本文列出的产品仅供研究使用，不适用于人类或临床诊断。我们产品所推荐应用，不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为，我们不承担任何责任。 |
| 其他 | 该抗体可检测内源蛋白 |
| 背景 | SREBF1 encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1， which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. Sterol regulatory element-binding protein 1 is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. |
Fig.1. Western Blot analysis of hela, HepG2 cells using SREBP-1 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.|||Abp53239-2.jpg
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